Commentary

SCIENCE: Teach creativity in science higher education 《SCIENCE》杂志浅谈育人之创造力的培养

Tony2024

科研能力的训练不仅包括'实战演习'，还有实战前的战略战术讨论——即创造性独立思考能力的培养

Nature: How to write a first-class paper

Tony2018

If science isn’t read, it doesn’t exist.

Nature: The strategy behind one of the most successful labs in the world

Tony2024

英国剑桥MRC分子生物学实验室———论科研文化与管理模式驱动科学进步的重要性

鲁白：原创科学研究靠的是什么？

Tony2024

科学家们在做创造性的工作的时候，整合信息和归纳性总结能力非常重要，除了努力，往往还需要想象力。当然鼓励大跨度交叉、坦诚地交流的环境更是至关重要。而原创的科学研究靠的是什么？当下我们的学生应该培养什么样的能力？好奇心、好学习、好探索、好研究，要有独立思考的能力。那什么样的科学工作才算是真正一流的基础研究？全球首创；打破传统理论体系；提出新概念，新理论，新方法；研发出颠覆性、普适性的技术。

赵国屏与合成生物学的故事

赵国屏2024

所谓的“胸怀大志”不仅仅是一个理想，更是一种对世界的理解和追求，这既包括“放眼世界”的世界观，也包括“阳光人生”的人生观，但最重要的是永远的“改造自己”，因为这是实现志向的必经之路。

Michael Fischbach Cell 杂志撰文：论科学选题的重要性！

Tony2024

Having observed that graduate students are taught almost everything about the theory and practice of science except how to pick a problem (研究生什么都教——从理论到实践——但鲜有老师或课程传授如何选题)

怎样做好技术驱动下的科学研究——听肖湘教授报告有感！

Hao Wu2024

不忘初心，砥砺前行；不忘初心，只争朝夕；不忘初心，方得始终！

SCIENCE: Nurturing Young Scientists for interdisciplinary researches

James Gentile, Sherwood Boehlert 2010

It will be important for this panel, and for universities, to recognize the value of early career scientists—the transformative discoveries they will make and the students they will influence—as key to America's future.

Nature's guide for mentors

Adrian Lee, Carina Dennis & Philip Campbell 2007

Having a good mentor early in one's career can mean the difference between success and failure in any career

Elements of a successful graduate study

Hao Wu2021

Make sure that you really want to devote yourself to science not just to get a PhD degree. Not everybody can be turned on by Science! If not, try something else.

Nature: Priorities for the next 10 years of human microbiome research

Lita Proctor2019

The dream of microbiome-based medicine requires a fresh approach — an ecological and evolutionary understanding of host-microbe interactions — argues Lita Proctor.

张启发院士给自己的博士生写的一封信

张启发

人生一世，应该追求有所建树。记得有一首诗：“朝为田舍郎，暮登天子堂。将相本无种，男儿当自强”。

Hao Wu2012

Keywords: bioinformatics, cardiometabolic diseases, microbiology, metagenomics, metabolomics, transcriptomics, omics integration, statistics, programming, NGS, bacterial evolution, machine learning

Karl Barry Sharpless: How to find something new?

Karl Barry Sharpless

American scientist who was cowinner of the Nobel Prize for Chemistry in 2001 and 2022. One for developing the first chiral catalysts and one for contributions to click chemistry and bioorthogonal chemistry.

Nature: Microbiome interventions for children raise the ethical stakes

Tony2024

Physicians are voicing concerns about a lack of regulation and the risks of parents taking matters into their own hands.

Science: 科研之路最重要的不是目的地，而是旅途中的每一次顿悟与成长

AIMShare2024

站在科研的漫漫长路上，我们既是求知者，也是成长者。那些看似的挫折与迷茫，终将成为照亮他人的灯塔。愿每一位科研工作者都能在这条充满挑战的道路上，既守护内心的热忱，又收获属于自己的精彩故事。在这个过程中，最重要的不是目的地，而是旅途中的每一次顿悟与成长。

记2024诺贝尔化学奖：How AI Revolutionized Protein Science, but Didn’t End It

Yasemin Saplakoglu2024

After saw alphafold2, John said: “Ugh, my favorite subject is dead” and Structural biology suddenly became unstructured.

John J. Hopfield talking about his research experience from solid state physics to biophysics and then to neuroscience, accidental?!

Tony2024

Physics was a point of view that the world around us is, with effort, ingenuity, and adequate resources, understandable in a predictive and reasonably quantitative fashion. Being a physicist is a dedication to the quest for this kind of understanding.

人民日报：深化教育综合改革

人民日报2024

“培养什么人、怎样培养人、为谁培养人是教育的根本问题，也是建设教育强国的核心课题”

吴家睿: 生命大科学：从微观到介观的组学研究

Tony2024

要真正揭开生命的奥秘，需要从整体角度来研究生命复杂系统的各种相互作用网络，以及相应的生理病理活动。

'Nature' comment: Boosting microbiome science worldwide could save millions of children’s lives

Tony 2023

Three steps to promote microbiome science!

Science: Giant project will chart human immune diversity to improve drugs and vaccines (人体免疫组计划)

Tony2024

Human Immunome Project aims to capture immune data from thousands of people globally

Scientific American: See Your Body’s Cells in Size and Number (人体细胞表型)

Tony

A new PNAS paper shows that the human cells follow the Zipf's law.

Human microbiome myths and misconceptions 人体微生物组领域相关的谜团及误解

Tony2023

Here we highlight selected human microbiome myths and misconceptions that lack a solid evidence base.

国家地理：Your gut health can affect the rest of your body. Here’s why.

CHRISTINA STERBENZ

Justin Sonnenburg: "It's a total pharmacy in there. It’s like we have a little drug factory in our guts. We're still kind of right at the beginning of understanding this. "

王晓东院士谈：如何选拔和培养顶尖科技创新人才？如何让青年科学家“冒尖”？

Tony2023

答案很简单：‘Empower Young People’——为年轻人赋能。”王晓东说，这些年北生所一直在做的，就是给最有创意、最有动力、最有能力但缺乏资源的青年科学家提供物质和心灵的自由，让他们全身心投入科研。

陈润生院士：中国生物信息学启蒙、传承的三十年「大江大河」

吴彤 (雷锋网)2023

生信长河中的群英图: 谈家桢（中国现代遗传学奠基人）、邹成鲁（近代中国生物化学的奠基人之一，时任中国科学院生物学部主任）、强伯勤（主要从事脑发育以及神经系统疾病相关基因的结构与功能研究）、陈竺（从事人类白血病和基因的研究）、罗辽复(80年代初由物理学向研究理论生物物理研究)、张春霆（80年代中期由物理学转而研究计算生物学和生物信息学）等

Nature: 文章越来越多，突破性文章越来越少

Hao Wu

Papers and patents are becoming less disruptive over time

NBE editorial: How to make cover letters instructive

吴浩2022-10

First, and foremost, know your audience.Second, help the editors understand and assess the main contributions of your work.Third, describe the realistic implications of the work.

Microbiology: Microbiome science needs a healthy dose of scepticism

William P. Hanage

To guard against hype, those interpreting research on the body's microscopic communities should ask five questions, says William P. Hanage.

金力院士：学科交叉已成为高水平科研与顶尖人才的重要特征

文汇报

不同学科的融合，表面上看是学科融合、学问融合，但核心是人与人之间的交流互动、思想碰撞、融合形成学术合力。

施一公：低年级硕博应该如何读英文文献？

吴浩

天外有天，读科研论文是一件很简单、但也很深奥的事情。一般的学生常常满足于读懂、读透一篇好的论文，优秀的学生则会举一反三、通过查找references纵深了解整个领域的历史、现状，并展望该领域未来的可能进展。

[视频] 从进化角度看肠道菌与人体互作之美

Hao Wu

记20年科研训练中所思、所见、所感

丘成桐和他的数学强国梦

韩扬眉2022

我这一辈子只有两个心愿，一个是成为大数学家，另外一个是提升祖国的数学，使它领导世界数学

Nature: creating a science legacy 科学家论传道受业解惑

Andy Tay2022

Senior academics offer tips to develop world-class research programmes and train successful protégés.

陈润生院士与他的生物信息学课程——33年未曾间断的声音

《国科大》2021

“当院士前后，从来没有任何区别”“我给自己取了个微信名，叫‘微不足道’”……一句句让人听得明白、透彻的话，从陈润生院士口中传出。80多岁的他仍站在讲台上，年复一年地讲给学生听，33年从未间断……

My lesson from successful scientists: success can be learnt

Ruth Gotian

High achievers are united in their passion for science, perseverance, hard work and lifelong learning, says Ruth Gotian.

How to tell a compelling story in scientific presentations

Nature

State your main finding in your title;‘But’ is good — use it for dramatic effect;Use repeated problems and solutions to create a story

Top journals that you should add to your reading/rss list

Hao Wu

Relevant journals to our lab research directions. This should be a good start to develop your reading habits (on a daily basis)

Why I swapped the piano for pipettes

By Jyoti Madhusoodanan

Nature Career: Concert pianist-turned-immunologist Gabriel Victora sees parallels between science and music.

Research Platforms at Human Phenome Institute (In Chinese)

HUPI2021

Phenomics, Genomics, Transcriptomics, Proteomics, Metabolomics, Metagenomics, Inflammatomics, etc

Nature milestones: Human microbiota research

Nature2019

Nature: twenty things I wish I’d known when I started my PhD

Lucy A. Taylor2018

Starting a PhD can be tough. Looking back, there are many things I wish I’d known at the beginning.

C. David Allis: On being an advisor to today’s junior scientists

Hao Wu

Excelling only at the bench does not make a complete scientist; our job is to make sure the training we provide does not stop there.

读博那几年

吴浩

在章张师兄和孟庆舒师姐的反复邮件叮嘱下，决定开写这篇札记以贺恩师于军教授六十大寿（有缘与于老师同日出生，也预祝自己生日快乐^_^）。章张师兄言：“都是于老师的思想继承者，好好写！”看此不免心生惭愧，只因传承于老师的太少

Inheritance of poor writing habits

Amin Bredan2022

Generations of editors, reviewers and readers have struggled to understand complex, exaggerated and often pompous prose that does little to enhance the reader's understanding

12 books recommended by Mu-ming Poo

Mu-ming Poo

Reading the first-hand account of the process of discovery by the discoverers themselves is probably the most effective way of learning how to do creative and original science.

Who is the best scientist of them all?

Richard Van Noorden 2013

Karl Marx is the most influential scholar ever, according to a discipline-corrected ranking system.

What did I learn during my PhD?

Hao Wu2012

The foreword of my thesis---a purely personal perspective (in Chinese)

The responsibility each of you has for your education

Barack Obama2009

And no matter what you want to do with your life, I guarantee that you'll need an education to do it. You want to be a doctor, or a teacher, or a police officer? You want to be a nurse or an architect, a lawyer or a member of our military? You're going to need a good education for every single one of those careers.

导航

Commentary