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Year
2018
2018
An integrated understanding of the rapid metabolic benefits of a carbohydrate-restricted diet on hepatic steatosis in humans
We show that the diet improves liver fat metabolism, promotes rapid shifts in the gut microbiota, increases circulating folate, and upregulates expression of genes involved in folate-dependent one carbon metabolism in the liver.
Cell Metabolism 27 (3), 559-571. e5
2018
VIEW
Microbially produced imidazole propionate impairs insulin signaling through mTORC1
Ara Koh et al identify imidazole propionate as a microbially produced histidine-derived metabolite that is present at higher concentrations in subjects with versus without type 2 diabetes.
Cell 175 (4), 947-961. e17
2018
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Topic
T2D
NAFLD
Metagenomics
Metabolomics
Metabolic diseases
Medication
Exercise
Heart failure
Diet
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