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Topic
Metagenomics
Metagenomics
Navigating the B vitamins: Dietary diversity, microbial synthesis, and human health
Here, we delve into the impact of these factors on B vitamins and introduce strategies,with a focus on microbiota-based therapeutic options, to enhance their availability for improved well-being.
Cell Host & Microbe
2024
VIEW
Spotlight: Unveiling Strain-Level Dynamics in Probiotic Activity
Divergent gene content among distinct probiotic strains contributes to varied or conflicting clinical efficacies.
Trends in Microbiology
2023
VIEW
Human Gut Microbiome Researches Over the Last Decade: Current Challenges and Future Directions
Eight selected challenges we are facing in human gut microbiome researches.
Phenomics
2023
VIEW
Microbially produced vitamin B12 contributes to the lipid-lowering effect of silymarin
Improvement of hepatic lipid metabolism by silymarin largely depends on gut microbes and their B12 producing ability.
Nature Communications 14, 477
2023
VIEW
The Gut Microbiota in Prediabetes and Diabetes: A Population-Based Cross-Sectional Study
Wu et al. now use two populations encompassing almost 1,500 subjects to demonstrate that the gut microbiota is altered in prediabetes and diabetes independent of diabetes medication.
Cell Metabolism, 32 (3), 379-390. e3
2020
VIEW
An integrated understanding of the rapid metabolic benefits of a carbohydrate-restricted diet on hepatic steatosis in humans
We show that the diet improves liver fat metabolism, promotes rapid shifts in the gut microbiota, increases circulating folate, and upregulates expression of genes involved in folate-dependent one carbon metabolism in the liver.
Cell Metabolism 27 (3), 559-571. e5
2018
VIEW
Microbially produced imidazole propionate impairs insulin signaling through mTORC1
Ara Koh et al identify imidazole propionate as a microbially produced histidine-derived metabolite that is present at higher concentrations in subjects with versus without type 2 diabetes.
Cell 175 (4), 947-961. e17
2018
VIEW
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T2D
NAFLD
Metagenomics
Metabolomics
Metabolic diseases
Medication
Exercise
Heart failure
Diet
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